Are Gout and diabetes friends in Need?How should gout amalgamate diabetes do?


Although gout and diabetes are completely different chronic diseases, they both belong to metabolic disorders and promote and develop each other.Most gout patients are accompanied by diabetes, conversely, many diabetic patients are accompanied by gout, how do the two affect?What is the relationship between gout and diabetes?1. Gout is easy to induce hypersaturation of blood uric acid in diabetes mellitus, when uric acid is extracted and deposited in joints, thus causing gout arthritis;If urate deposition in the kidney, can induce uric acid kidney stones or nephropathy;If urate deposits in blood vessels, it is easy to cause atherosclerosis;If urate deposition in islet can damage islet B cells, insulin secretion decreased.Urate deposition in islet B cells, muscle or peripheral tissue can reduce the sensitivity of target cells to insulin, induce or aggravate insulin resistance, easy to cause abnormal glucose metabolism, and thus induce diabetes.2. Diabetes is easy to induce gout. Many diabetic patients have abnormal kidney function, especially type 2 diabetes. After renal function is damaged, renal glucose threshold can be reduced.Most diabetics are accompanied by obesity, high blood pressure and insulin resistance, and these adverse factors can induce gout.Obesity, in particular, is prone to insulin resistance, leading to hyperinsulinemia, promoting the synthesis of uric acid in the liver, and also inhibiting the excretion of uric acid through the kidney, resulting in increased uric acid level in the blood.How should gout amalgamate diabetes do?1. Select appropriate uric-lowering drugs for gout patients with diabetes. Non-steroidal anti-inflammatory drugs or colchicine can be used for pain relief in the acute stage of gout, but small doses should be used.Glucocorticoids should not be used because they can raise blood sugar.Patients with gout combined with diabetes have poor renal function and cannot take allopurinol in large doses for a long time.When taking benbromarone, urine should be alkalized, but it should not be used in patients with severe renal impairment, otherwise it will increase the burden on the kidney.2, rational selection of hypoglycemic drugs Because hypoglycemic drugs can affect the level of blood uric acid, so we must be careful when choosing drugs.For example, insulin can accelerate the synthesis of uric acid through the liver, block the excretion of uric acid through the kidney, and thus increase the level of blood uric acid. Therefore, patients with gout complicated with diabetes should carefully choose insulin.Metformin is a good choice, not only to lower blood sugar, but also to improve kidney function, blood uric acid metabolism rate.3. Adjust the lifestyle and strictly control the daily total calorie intake, and do a good match of meat and vegetables and their thickness.Stay away from high-sugar foods such as drinks, cakes or cakes, and eat less high-sugar fruits to avoid raising blood uric acid and blood sugar levels.At the same time to control fat and protein intake, smoking and alcohol;Eat more fresh vegetables such as pakchoi, eggplant and rape;Make sure to drink more than 2000 ml of water per day, which can help uric acid excretion, but patients with impaired kidney function should limit the amount of water intake.Warm reminder The main symptoms of gout combined with diabetes are polydipsia, polyuria, weight loss, fatigue, post-meal palpitation, hunger and hand tremor, etc. In this case, we should go to the hospital for relevant examination and treatment in time, so as not to induce other vascular complications.It is worth noting that the treatment of diabetes should stabilize blood uric acid level, which can protect insulin function, reduce insulin sensitivity, and prevent the occurrence of diabetic nephropathy.Family doctor online special article, shall not be reproduced without authorization

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